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Why the shortage?
There are several reasons. Only a small proportion of people die in a way which makes their organs suitable for transplantation in the hospital, preferably in an intensive care unit, following a road accident or a stroke. Some have not made it clear that they wish to donate their organs when they die, and relatives may be too upset to give permission or doctors too embarrassed to ask.

Ironically, road safety campaigns and improved stroke treatments have helped reduce the supply of organ donors. Yet, success rates for transplant surgery continue to rise. In 1985, six out of 10 people lived a year or more after a heart transplant. By 1997, the figure had risen to 84%. For kidney transplant the figure rose from 70% up to 85% in the same period.

So skilled are the transplant teams that surgeons would operate on older, sicker patients than ever before – if only there were enough human organs to go around.
Who is waiting for a transplant?
Why the shortage?
Why are transplanted organs rejected?
What is xenotransplantation?
Why Xenotransplantation and what are its potential benefits?
What animals would be used for xenotransplants?
Have animal organs or tissues been used in humans before?
What are the potential risks of xenotransplantation?
How are scientists trying to prevent hyperacute rejection of xenotransplants?
What is a Transgenic animal?
Have transgenic pigs got rid of the rejection problems for xenotransplants?
Can transgenic pig organs be transplanted into humans?
Do pig organs carry potentially infectious agents such as viruses that could be transmitted to human recipients?
What is a retrovirus?
Have PERVs put an end to pig to human transplants then? Has PERV ever been transmitted to a human?
Is xenotransplantation the only solution to the shortage of organs for transplantation?
What is Reproductive Cloning?
What is Transfection?
What is Nucleofection?
Are pig cells transplanted into brains likely to behave in the same way as human cells?
Can pig nerve cells survive in the brain?
To repair brain damage, are pig cells better than stem cells?
Is the XENOME Project concerned about the welfare of animals?