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Can transgenic pig organs be transplanted into humans?
No organs from transgenic pigs have been transplanted into humans. There are very strict requirements that need to be met prior to approval by national regulatory bodies of novel clinical approaches. In particular authorities want to be assured of the results with transgenic pig organs in non-human primates before they will give the go-ahead for the initiation of experimental clinical trials. Public acceptance of this procedure will also be essential. Furthermore, there is also the need to demonstrate that pig organs will not lead to infections once transplanted into primates.
Who is waiting for a transplant?
Why the shortage?
Why are transplanted organs rejected?
What is xenotransplantation?
Why Xenotransplantation and what are its potential benefits?
What animals would be used for xenotransplants?
Have animal organs or tissues been used in humans before?
What are the potential risks of xenotransplantation?
How are scientists trying to prevent hyperacute rejection of xenotransplants?
What is a Transgenic animal?
Have transgenic pigs got rid of the rejection problems for xenotransplants?
Can transgenic pig organs be transplanted into humans?
Do pig organs carry potentially infectious agents such as viruses that could be transmitted to human recipients?
What is a retrovirus?
Have PERVs put an end to pig to human transplants then? Has PERV ever been transmitted to a human?
Is xenotransplantation the only solution to the shortage of organs for transplantation?
What is Reproductive Cloning?
What is Transfection?
What is Nucleofection?
Are pig cells transplanted into brains likely to behave in the same way as human cells?
Can pig nerve cells survive in the brain?
To repair brain damage, are pig cells better than stem cells?
Is the XENOME Project concerned about the welfare of animals?